Presentación    
ESTRATEGIAS NEUROPROTECTORAS
EN ENFERMEDADES NEURODEGENERATIVAS
Publicaciones

Publicaciones 2014
DOCUMENTO F.I. CUARTIL
Hernández, C.; García-Ramírez, M.; García-Rocha, M.; Sáez-López, C.; Valverde, A. M.; Guinovart, J. J.; Simo, R. Glycogen storage in the human retinal pigment epithelium: a comparative study of diabetic and non-diabetic donors. ACTA DIABETOLOGICA. 2014; 51(4): 543-552. Artículo. 2,399 Q3
Rojo, A. I.; Rada, P.; Mendiola, M.; Ortega-Molina, A.; Wojdyla, K.; Rogowska-Wrzesinska, A.; Hardisson, D.; Serrano, M.; Cuadrado, A.The PTEN/NRF2 axis promotes human carcinogenesis. ANTIOXIDANTS & REDOX SIGNALING. 2014; 21(18): 2498-2514. Artículo. 7,407 D1
Mobasher, M. A.; Valverde, A. M. Signalling pathways involved in paracetamol-induced hepatotoxicity: new insights on the role of protein tyrosine phosphatase 1B. ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY. 2014; 120(2): 51-63. Artículo. 1,763 Q3
Lastres-Becker, I.; Innamorato, N. G.; Jaworski, T.; Rabano, A.; Kugler, S.; Van Leuven, F.; Cuadrado, A. Fractalkine activates NRF2/NFE2L2 and heme oxygenase 1 to restrain tauopathy-induced microgliosis. BRAIN. 2014; 137(1): 78-91. Artículo. 9,196
D1
González-Rodríguez, A.; Mayoral, R.; Agra, N.; Valdecantos, M. P.; Pardo, V.; Miquilena-Colina, M. E.; Vargas-Castrillón, J.; lo Iacono, O.; Corazzari, M.; Fimia, G. M.; Piacentini, M.; Muntane, J.; Boscá, L.; García-Monzón, C.; Martín-Sanz, P.; Valverde, A. M. Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD. CELL DEATH & DISEASE. 2014; 5: e1179. Artículo. 5,014 Q2
Través, P. G.; Pardo, V.; Pimentel-Santillana, M.; González-Rodríguez, A.; Mojena, M.; Rico, D.; Montenegro, Y.; Calés, C.; Martín-Sanz, P.; Valverde, A. M.; Boscá, L. Pivotal role of protein tyrosine phosphatase 1B (PTP1B) in the macrophage response to pro-inflammatory and antiinflammatory challenge. CELL DEATH & DISEASE. 2014; 5: e1125. Artículo. 5,014 Q2
González-Rodríguez, A.; Reibert, B.; Amann, T.; Constien, R.; Rondinone, C. M.; Valverde, A. M. In vivo siRNA delivery of Keap1 modulates death and survival signaling pathways and attenuates concanavalin-A-induced acute liver injury in mice. DISEASE MODELS & MECHANISMS. 2014; 7(9): 1093-1100. Artículo. 4,973 D1
Mobasher, M. A.; de Toro-Martín, J.; González-Rodríguez, A.; Ramos, S.; Letzig, L. G.; James, L. P.; Muntane, J.; Álvarez, C.; Valverde, A. M. Essential role of protein-tyrosine phosphatase 1b in the modulation of insulin signaling by acetaminophen in hepatocytes. JOURNAL OF BIOLOGICAL CHEMISTRY. 2014; 289(42): 29406-29419. Artículo. 4,573 Q1
Cuadrado, A.; Martín-Moldes, Z.; Ye, J. P.; Lastres-Becker, I. Transcription factors NRF2 and NF-kappa B are coordinated effectors of the Rho family, GTP-binding protein RAC1 during inflammation. JOURNAL OF BIOLOGICAL CHEMISTRY. 2014; 289(22): 15244-15258. Artículo. 4,573 Q1
Parada, E.; Buendía, I.; León, R.; Negredo, P.; Romero, A.; Cuadrado, A.; López, M. G.; Egea, J. Neuroprotective effect of melatonin against ischemia is partially mediated by alpha-7 nicotinic receptor modulation and HO-1 overexpression. JOURNAL OF PINEAL RESEARCH. 2014; 56(2): 204-212. Artículo. 9,6 D1
Simón, D.; Herva, M. E.; Benítez, M. J.; Garrido, J. J.; Rojo, A. I.; Cuadrado, A.; Torres, J. M.; Wandosell, F. Dysfunction of the PI3K-Akt-GSK-3 pathway is a common feature in cell culture and in vivo models of prion disease. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. 2014; 40(3): 311-326. Artículo. 3,927 Q1
Ibáñez, L.; Ferrándiz, M. L.; Brines, R.; Guede, D.; Cuadrado, A.; Alcaraz, M. J. Effects of Nrf2 deficiency on bone microarchitecture in an experimental model of osteoporosis. OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. 2014; 726590. Artículo. 3,516 Q2
Rojo, A. I.; McBean, G.; Cindric, M.; Egea, J.; López, M. G.; Rada, P.; Zarkovic, N.; Cuadrado, A. Redox control of microglial function: molecular mechanisms and functional significance. ANTIOXIDANTS & REDOX SIGNALING. 2014; 21(12): 1766-1801. Revisión. 7,407 D1
Simó, R.; Hernández C.; et al. European Consortium for the Early
Treatment of Diabetic Retinopathy (EUROCONDOR) (Valverde, A.M.). Neurodegeneration in the diabetic eye: new insights and therapeutic perspectives. TRENDS IN ENDOCRINOL AND METABOLISM. 2014; 25(1): 23-33. Revisión.
9,392 D1
Publicaciones 2009 - 2013
AÑO DENOMINACIÓN F.I. CUARTIL
2013 Hale, L.; Hurcombe, J.; Lay, A.; Santamaría, B.; Valverde, A.
M.; Saleem, M. A.; Mathieson, P. W.; Welsh, G. I.; Coward, R. J.
Insulin directly stimulates VEGF-A production in the glomerular
podocyte. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 2013; 305(2): F182-F188. Artículo.
3,3 Q1
2013 Samino, S.; Revuelta-Cervantes, J.; Vinaixa, M.; Rodríguez, M.
A.; Valverde, A. M.; Correig, X. A H-1 NMR metabolic profiling
to the assessment of protein tyrosine phosphatase 1B role in liver
regeneration after partial hepatectomy. BIOCHIMIE. 2013; 95(4): 808-816. Artículo.
3,123 Q2
2013 Mobasher, M. A.; González-Rodríguez, A.; Santamaría, B.; Ramos,
S.; Martín, M. A.; Goya, L.; Rada, P.; Letzig, L.; James, L. P.; Cuadrado, A.; Martín-Pérez, J.; Simpson, K. J.; Muntane, J.; Valverde, A. M. Protein tyrosine phosphatase 1B modulates GSK3 beta/Nrf2 and IGFIR signaling pathways in acetaminophen-induced hepatotoxicity. CELL DEATH & DISEASE. 2013; 4: e626. Artículo.
5,177 Q1
  Carneado, J.; Farrera-Sinfreu, J.; Ponsati, B.; González-Rodríguez,
A.; Valverde, A. M.; Simo, R. Topical administration of somatostatin prevents retinal neurodegeneration in experimental diabetes. DIABETES. 2013; 62(7): 2569-2578. Artículo.
8,474 D1
2013 Arroba, A. I.; Revuelta-Cervantes, J.; Menes, L.; González-
Rodríguez, A.; Pardo, V.; de la Villa, P.; Burks, D. J.; Valverde,
A. M. Loss of protein tyrosine phosphatase 1B increases IGF-I
receptor tyrosine phosphorylation but does not rescue retinal defects in IRS2-deficient mice. INVESTIGATIVE OPHTHALMOLOGY
& VISUAL SCIENCE. 2013; 54(6): 4215-4224. Artículo.
3,661 Q1
2013 Sanz-García, C.; Ferrer-Mayorga, G.; González-Rodríguez, A.;
Valverde, A. M.; Martín-Duce, A.; Velasco-Martín, J. P.; Regadera,
J.; Fernández, M.; Alemany, S. Sterile inflammation in acetaminophen-induced liver injury is mediated by Cot/tpl2. JOURNAL OF BIOLOGICAL CHEMISTRY. 2013; 288(21): 15342-15351. Artículo.
4,6 Q1
2013 García-Yagüe, A. J.; Rada, P.; Rojo, A. I.; Lastres-Becker, I.; Cuadrado, A. Nuclear import and export signals control the subcellular localization of Nurr1 protein in response to oxidative
stress. JOURNAL OF BIOLOGICAL CHEMISTRY. 2013; 288(8): 5506-5517. Artículo.
4,6 Q1
2013 Frances, D. E. A.; Ingaramo, P. I.; Mayoral, R.; Través, P.; Casado,
M.; Valverde, A. M.; Martín-Sanz, P.; Carnovale, C. E. Cyclooxygenase-2 over-expression inhibits liver apoptosis nduced by hyperglycemia. JOURNAL OF CELLULAR BIOCHEMISTRY.
2013; 114(3): 669-680. Artículo.
3,368 Q2
2013 González-Terán, B.; Cortés, J. R.; Manieri, E.; Matesanz, N.; Verdugo, .; Rodríguez, M. E.; González-Rodríguez, A.; Valverde,
A.; Martin, P.; Davis, R. J.; Sabio, G. Eukaryotic elongation factor
2 controls TNF-alpha translation in LPS-induced hepatitis. OURNAL OF CLINICAL INVESTIGATION. 2013; 123(1): 164-178. Artículo.
13,765 D1
2013 Uzi, D.; Barda, L.; Scaiewicz, V.; Mills, M.; Mueller, T.; González-
Rodríguez, A.; Valverde, A. M.; Iwawaki, T.; Nahmias, Y.; Xavier,
R.; Chung, R. T.; Tirosh, B.; Shibolet, O. CHOP is a critical regulator of acetaminophen-induced hepatotoxicity. JOURNAL
OF HEPATOLOGY. 2013; 59(3): 495-503. Artículo.
10,401 D1
2013 Drost, J.; Nonis, D.; Eich, F.; Leske, O.; Damrath, E.; Brunt, E.
R.; Lastres-Becker, I.; Heumann, R.; Nowock, J.; Auburger, G.
Ataxin-2 modulates the levels of Grb2 and SRC but not RAS
signaling. JOURNAL OF MOLECULAR NEUROSCIENCE. 2013; 51(1): 68-81. Artículo.
2,757 Q3
2013 Vida, M.; Serrano, A.; Romero-Cuevas, M.; Pavón, F. J.; González-Rodríguez, A.; Gavito, A. L.; Cuesta, A. L.; Valverde, A. M.; de Fonseca, F. R.; Baixeras, E. IL-6 cooperates with peroxisome proliferator-activated receptor-alpha-ligands to induce
liver fatty acid binding protein (LFABP) up-regulation. LIVER INTERNATIONAL. 2013; 33(7): 1019-1028. Artículo.
4,412 Q1
2013 Valverde, A. M.; Miranda, S.; García-Ramírez, M.; González-
Rodríguez, A.; Hernández, C.; Simo, R. Proapoptotic and survival
signaling in the neuroretina at early stages of diabetic retinopathy. MOLECULAR VISION. 2013; 19: 47-53. Artículo.
2,245 Q2
2013 Chowdhry, S.; Zhang, Y.; McMahon, M.; Sutherland, C.; Cuadrado, A.; Hayes, J. D. Nrf2 is controlled by two distinct beta-
TrCP recognition motifs in its Neh6 domain, one of which can
be modulated by GSK-3 activity. ONCOGENE. 2013; 32(32):
3765-3781. Artículo.
8,559 D1
2013 Martín-de-Saavedra, M. D.; Budni, J.; Cunha, M. P.; Gómez-
Rangel, V.; Lorrio, S.; del Barrio, L.; Lastres-Becker, I.; Parada,
E.; Tordera, R. M.; Rodrigues, A. L. S.; Cuadrado, A.; López, M.
G. Nrf2 participates in depressive disorders through an antiinflammatory mechanism. PSYCHONEUROENDOCRINOLOGY. 2013; 38(10): 2010-2022. Artículo.
5,591 D1
2013 Tobón-Velasco, J. C.; Limón-Pacheco, J. H.; Orozco-Ibarra,
M.; Macías-Silva, M.; Vázquez-Victorio, G.; Cuevas, E.; Ali, S.
F.; Cuadrado, A.; Pedraza-Chaverri, J.; Santamaría, A. 6-OHDA-
induced apoptosis and mitochondrial dysfunction are mediated by early modulation of intracellular signals and interaction of Nrf2 and NF-kappa B factors. TOXICOLOGY. 2013; 304: 109-119. Artículo.
3,745 Q1
2013 Hernández-Breijo, B.; Monserrat, J.; Román, I. D.; González-Rodríguez, A.; Fernández-Moreno, M. D.; Lobo, M. V. T.; Valverde, A. M.; Gisbert, J. P.; Guijarro, L. G. Azathioprine desensitizes liver cancer cells to insulin-like growth factor 1 and
causes apoptosis when it is combined with bafilomycin A1.
TOXICOLOGY AND APPLIED PHARMACOLOGY. 2013; 272(3): 568-578. Artículo.
3,63 Q1
2012 González-Rodríguez, A.; Mas-Gutiérrez, J. A.; Mirasierra, M.; Fernández-Pérez, A.; Lee, Y. J.; Ko, H. J.; Kim, J. K.; Romanos, E.; Carrascosa, J. M.; Ros, M.; Vallejo, M.; Rondinone, C. M.; Valverde, A. M. Essential role of protein tyrosine phosphatase 1B in obesity-induced infl ammation and peripheral insulin resistance during aging. AGING CELL. 2012; 11(2): 284-296. Article. 5,705 D1
2012 Burgos-Ramos, E.; González-Rodríguez, A.; Canelles, S.; Baquedano, E.; Frago, L. M.; Revuelta-Cervantes, J.; Gómez-Ambrosi, J.; Fruhbeck, G.; Chowen, J. A.; Argente, J.; Valverde, A. M.; Barrios, V. Differential insulin receptor substrate-1 (IRS1)-Related modulation of neuropeptide y and proopiomelanocortin expression in nondiabetic and siabetic IRS2(-/-) mice. ENDOCRINOLOGY. 2012; 153(3): 1129-1140. Article. 4,717  Q1
2012 Rojo, A. I.; Medina-Campos, O. N.; Rada, P.; Zúñiga-Toala, A.; López-Gazcón, A.; Espada, S.; Pedraza-Chaverri, J.; Cuadrado, A. Signaling pathways activated by the phytochemical nordihydroguaiaretic acid contribute to a keap1-independent regulation of Nrf2 stability: Role of glycogen synthase kinase-3. FREE RADICAL BIOLOGY AND MEDICINE. 2012; 52(2): 473-487. Article. 5,271 Q1
2012 Martín-Moreno, A. M.; Brera, B.; Spuch, C.; Carro, E.; García-García, L.; Delgado, M.; Pozo, M. A.; Innamorato, N. G.; Cuadrado, A.; de Ceballos, M. L. Prolonged oral cannabinoid administration prevents neuroinfl ammation, lowers betaamyloid levels and improves cognitive performance in Tg APP 2576 mice. JOURNAL OF NEUROINFLAMMATION. 2012; 9: 8. Article. 4,351  Q1
2012 Rada, P.; Rojo, A. I.; Evrard-Todeschi, N.; Innamorato, N. G.; Cotte, A.; Jaworski, T.; Tobón-Velasco, J. C.; Devijver, H.; García-Mayoral, M. F.; Van Leuven, F.; Hayes, J. D.; Bertho, G.; Cuadrado, A. Structural and functional characterization of Nrf2 degradation by the glycogen synthase kinase 3/beta-TrCP axis. MOLECULAR AND CELLULAR BIOLOGY. 2012; 32(17): 3486-3499. Article. 5,372 Q1
2012 Murillo-Cuesta, S.; Camarero, G.; González-Rodríguez, A.; Rodríguez-de la Rosa, L.; Burks, D. J.; Avendaño, C.; Valverde, A. M.; Varela-Nieto, I. Insulin receptor substrate 2 (IRS2)-Defi cient mice show sensorineural hearing loss that is delayed by concomitant protein tyrosine phosphatase 1B
(PTP1B) Loss of function. MOLECULAR MEDICINE. 2012; 18(2): 260-269. Article.
4,469 Q1
2012 Tobón-Velasco, J. C.; Vázquez-Victorio, G.; Macías-Silva, M.; Cuevas, E.; Ali, S. F.; Maldonado, P. D.; González-Trujano, M. E.; Cuadrado, A.; Pedraza-Chaverri, J.; Santamaría, A. Sallyl cysteine protects against 6-hydroxydopamine-induced neurotoxicity in the rat striatum: Involvement of Nrf2 transcription factor activation and modulation of signaling kinase
cascades. FREE RADICAL BIOLOGY AND MEDICINE. 2012; 53(5): 1024-1040. Article.
5,271 Q1
2012 Lastres-Becker, I.; Ulusoy, A.; Innamorato, N. G.; Sahin, G.; Rabano, A.; Kirik, D.; Cuadrado, A. Alpha-Synuclein expression and Nrf2 defi ciency cooperate to aggravate protein aggregation, neuronal death and infl ammation in early-stage Parkinson’s disease. HUMAN MOLECULAR GENETICS. 2012; 21(14): 3173-3192. Article. 7,692  D1
2012 Ortega-Molina, A.; Efeyan, A.; López-Guadamillas, E.; Muñoz-Martín, M.; Gómez-López, G.; Canamero, M.; Mulero, F.; Pastor, J.; Martínez, S.; Romanos, E.; González-Barroso, M.M.; Rial, E.; Valverde, A. M.; Bischoff, J. R.; Serrano, M. Ptenpositively regulates brown adipose function, energy expenditure, and longevity. CELL METABOLISM. 2012; 15(3): 382-394. Article. 14,619  D1
2012 García-Ruiz, I.; Solís-Muñoz, P.; Gómez-Izquierdo, E.; Muñoz-Yagüe, M. T.; Valverde, A. M.; Solís-Herruzo, J. A. Proteintyrosine phosphatases are involved in Interferon resistance associated with insulin resistance in HepG2 cells and obesemice. JOURNAL OF BIOLOGICAL CHEMISTRY. 2012; 287(23): 19564-19573. Article. 4,651 Q1
2012 Ortiz, C.; Caja, L.; Bertrán, E.; González-Rodríguez, A.; Valverde, A. M.; Fabregat, I.; Sancho, P. Protein-Tyrosine Phosphatase 1B (PTP1B) defi ciency confers resistance to transforming growth factor-beta (TGF-beta)-induced suppressor effects in hepatocytes. JOURNAL OF BIOLOGICAL CHEMISTRY. 2012; 287(19): 15263-15274. Article. 4,651  Q1
2012 Miranda, S.; González-Rodríguez, A.; García-Ramírez, M.; Revuelta-Cervantes, J.; Hernández, C.; Simo, R.; Valverde, A. M. Benefi cial effects of fenofi brate in retinal pigment epithelium by the modulation of stress and survival signaling under diabetic conditions. JOURNAL OF CELLULAR PHYSIOLOGY. 2012; 227(6): 2352-2362. Article.  4,218  Q1
2012 Ardiles, A. E.; Rodríguez, A. G.; Núñez, M. J.; Perestelo, N.R.; Pardo, V.; Jiménez, I. A.; Valverde, A. M.; Bazzocchi, I. L. Studies of naturally occurring friedelane triterpenoids as insulin sensitizers in the treatment type 2 diabetes mellitus. PHYTOCHEMISTRY. 2012; 84: 116-124. Article.  3,05 Q1
2012 Simo, R.; Hernández, C. Neurodegeneration is an early event in diabetic retinopathy: therapeutic implications. BRITISH JOURNAL OF OPHTHALMOLOGY. 2012; 96(10): 1285-1290. Review. 2,725 Q1
2011 Martín-Moreno, A. M.; Reigada, D.; Ramírez, B. G.; Mechoulam, R.; Innamorato, N.; Cuadrado, A.; de Ceballos, M. L. Cannabidiol and Other Cannabinoids Reduce Microglial Activation In Vitro and In Vivo: Relevance to Alzheimer’s Disease. MOLECULAR PHARMACOLOGY. 2011; 79(6): 964-973. Article.  4,883 D1
2011 Merino, J. J.; Montes, M. L.; Blanco, A.; Bustos, M. J.; Oreja-Guevara,
C.; Bayón, C.; Cuadrado, A.; Lubrini, G.; Cambrón, I.; Muñoz, A.; Cebolla,
S.; Gutiérrez-Fernández, M.; Bernardino, J. I.; Arribas, J. R.; Fiala, M. HIV-1 neuropathogenesis: therapeutic strategies against neuronal loss induced by gp120/Tat glycoprotein in the central nervous system. REVISTA DE NEUROLOGÍA. 2011; 52(2): 101-111. Article.
0,652 Q4
2011 Granado, N.; Lastres-Becker, I.; Ares-Santos, S.; Oliva, I.; Martín, E.;
Cuadrado, A.; Moratalla, R. Nrf2 Deficiency Potentiates Methamphetamine-
Induced Dopaminergic Axonal Damage and Gliosis in
the Striatum. GLIA. 2011; 59(12): 1850-1863. Article
4,82 Q1
2011 Jazwa, A.; Rojo, A. I.; Innamorato, N. G.; Hesse, M.; Fernández-Ruiz, J.;
Cuadrado, A. Pharmacological Targeting of the Transcription Factor
Nrf2 at the Basal Ganglia Provides Disease Modifying Therapy for
Experimental Parkinsonism. ANTIOXIDANTS & REDOX SIGNALING.
2011; 14(12): 2347-2360. Article.
8,456 D1
2011 Rada, P.; Rojo, A. I.; Chowdhry, S.; McMahon, M.; Hayes, J. D.; Cuadrado, A. SCF/beta-TrCP Promotes Glycogen Synthase Kinase 3-Dependent Degradation of the Nrf2 Transcription Factor in a Keap1-
Independent Manner. MOLECULAR AND CELLULAR BIOLOGY.
2011; 31(6): 1121-1133. Article.
5,527 Q1
2010 Rojo, A. I.; Innamorato, N. G.; Martín-Moreno, A. M.; De Ceballos, M. L.; Yamamoto, M.; Cuadrado, A. Nrf2 Regulates Microglial Dynamics and Neuroinflammation in Experimental Parkinson's Disease. GLIA. 2010; 58(5): 588-598. Article.   5,186 Q1
2010 nnamorato, N. G.; Jazwa, A.; Rojo, A. I.; García, C.; Fernández-Ruiz, J.; Grochot-Przeczek, A.; Stachurska, A.; Jozkowicz, A.; Dulak, J.; Cuadrado, A. Different Susceptibility to the Parkinson's Toxin MPTP in Mice Lacking the Redox Master Regulator Nrf2 or Its Target Gene Heme Oxygenase-1. PLOS ONE. 2010; 5(7): e11838. Article.  4,411 Q1
2010  
Espada, S.; Ortega, F.; Molina-Jijon, E.; Rojo, A. I.; Pérez-Sen, R.; Pedraza-Chaverri, J.; Miras-Portugal, M. T.; Cuadrado, A. The purinergic P2Y(13) receptor activates the Nrf2/HO-1 axis and protects against oxidative stress-induced neuronal death. FREE RADICAL BIOLOGY AND MEDICINE. 2010; 49(3): 416-426. Article. 
5,707 Q1
2010 Niso-Santano, M.; González-Polo, R. A.; Bravo-San Pedro, J. M.; Gómez-Sánchez, R.; Lastres-Becker, I.; Ortiz-Ortiz, M. A.; Soler, G.; Morán, J. M.; Cuadrado, A.; Fuentes, J. M. Activation of apoptosis signal-regulating kinase 1 is a key factor in paraquat-induced cell death: Modulation by the Nrf2/Trx axis. FREE RADICAL BIOLOGY AND MEDICINE. 2010; 48(10): 1370-1381. Article 5,707 Q1
2010 Flores, J. A., Galán-Rodríguez, B.; Rojo, A. I.; Ramiro-Fuentes, S.; Cuadrado, A.: Fernández-Espejo, E. Fibroblast growth factor-1 within the ventral tegmental area  participates in motor sensitizing effects of morphine. NEUROSCIENCE. 2010; 13; 165(1):198-211. Article.  3,215 Q2
2010 Jazwa, A.; Cuadrado, A. Targeting heme oxygenase-1 for neuroprotection and neuroinflammation in neurodegenerative diseases CURRENT DRUG TARGETS. 2010. 11(12):1517-31. Review.  3,061  Q2
2009 Megias, J; Guillen, MI; Clerigues, V; Rojo, AI; Cuadrado, A; Castejon, MA; Gomar, F; Alcaraz, MJ.Heme oxygenase-1 induction modulates microsomal prostaglandin E synthase-1 expression and prostaglandin E-2 production in osteoarthritic chondrocytes. BIOCHEMICAL PHARMACOLOGY. 2009; 77(12): 1806-1813 4,254
Q1
2009 Innamorato, NG; Lastres-Becker, I; Cuadrado, A.Role of microglial redox balance in modulation of neuroinflammation. CURRENT OPINION IN NEUROLOGY. 2009; 22(3): 308-314 5,430
Q1
2009 Cuadrado, A; Moreno-Murciano, P; Pedraza-Chaverri, J.The transcription factor Nrf2 as a new therapeutic target in Parkinson's disease. EXPERT OPINION ON THERAPEUTIC TARGETS. 2009; 13(3): 319-329 3,713
Q1
2009 Sagredo, O; Gonzalez, S; Aroyo, I; Pazos, MR; Benito, C; Lastres-Becker, I; Romero, JP; Tolon, RM; Mechoulam, R; Brouillet, E; Romero, J; Fernandez-Ruiz, J.Cannabinoid CB2 Receptor Agonists Protect the Striatum Against Malonate Toxicity: Relevance for Huntington's Disease. GLIA. 2009; 57(11): 1154-1167 4,932
Q1
2009 Espada, S; Rojo, AI; Salinas, M; Cuadrado, A.The muscarinic M1 receptor activates Nrf2 through a signaling cascade that involves protein kinase C and inhibition of GSK-3beta: connecting neurotransmission with neuroprotection. JOURNAL OF NEUROCHEMISTRY. 2009; 110(3): 1107-1119 3,999
Q1
2009 Egea, J; Rosa, AO; Lorrio, S; del Barrio, L; Cuadrado, A; Lopez, MG.Haeme oxygenase-1 overexpression via nAChRs and the transcription factor Nrf2 has antinociceptive effects in the formalin test. PAIN. 2009; 146(40210): 75-83 5,371
Q1