Presentación    
INVOLVEMENT OF GLYCINERGIC AND GLUTAMATERGIC SYSTEMS IN CENTRAL NERVOUS SYSTEM PATHOLOGIES
Publications

Publications 2014
DOCUMENTO F.I. CUARTIL
Barthel, F.; Urban, A.; Schlosser, L.; Eulenburg, V.; Werdehausen, R.; Brandenburger, T.; Aragón, C.; Bauer, I.; Hermanns, H. Long-term application of glycine transporter inhibitors acts antineuropathic and modulates spinal N-methyl-D-aspartate receptor subunit NR-1 expression in rats. ANESTHESIOLOGY. 2014; 121(1): 160-169. Artículo. 5,879 D1
de Juan-Sanz, J.; Núñez, E.; Zafra, F.; Berrocal, M.; Corbacho, I.; Ibáñez, I.; Arribas-González, E.; Marcos, D.; López-Corcuera, B.; Mata, A.M.; Aragón, C. Presynaptic control of glycine transporter 2 (GlyT2) by physical and functional association with plasma membrane Ca2+-ATPase (PMCA) and Na+-Ca2+ exchanger (NCX). JOURNAL OF BIOLOGICAL CHEMISTRY. 2014; 289(49): 34608-34324. Artículo. 4,573 Q1
Jiménez, E; Núñez, E.; Ibáñez, I.; Draffin, J. E.; Zafra, F.; Giménez, C. Differential regulation of the glutamate transporters GLT-1 and GLAST by GSK3 beta. NEUROCHEMISTRY INTERNATIONAL. 2014; 79: 33-43. Artículo. 3,092 Q2
Rodríguez, A.; Ortega, A.; Berumen, L. C.; García-Alcocer, M. G.; Giménez, C.; Zafra, F. Expression of the system N transporter (SNAT5/ SN2) during development indicates its plausible role in glutamatergic neurotransmission. NEUROCHEMISTRY INTERNATIONAL. 2014; 73: 166-171. Artículo. 3,092 Q2
Cubelos, B.; Leite, C.; Giménez, C.; Zafra, F. Localization of the glycine transporter GLYT1 in glutamatergic synaptic vesicles. NEUROCHEMISTRY INTERNATIONAL. 2014; 73: 204-210. Artículo. 3,092 Q2
Publications 2009 - 2013
YEAR NAME I.F. QUARTILE
2013 de Juan-Sanz, J.; Núñez, E.; López-Corcuera, B.; Aragón, C. Regulation of the glycinergic neurotransmission during inflammatory pain: a new pathway in the action of Prostaglandin E2 in the spinal cord. ANALES DE LA REAL ACADEMIA NACIONAL DE FARMACIA. 2013; 79(3): 434-449.  Artículo. No Indexado No Indexado
2013 de Juan-Sanz, J.; Núñez, E.; Villarejo-López, L.; Pérez-Hernández,
D.; Rodríguez-Fraticelli, A. E.; López-Corcuera, B.; Vázquez, J.; Aragón, C. Na+/K+-ATPase Is a new interacting partner for the neuronal glycine transporter GlyT2 that downregulates its expression in vitro and in vivo. JOURNAL OF NEUROSCIENCE. 2013; 33(35): 14269-14281.  Artículo.
6,747 D1
2013 Arribas-González, E.; Alonso-Torres, P.; Aragón, C.; López-Corcuera,
B. Calnexin-assisted biogenesis of the neuronal glycine transporter 2 (GlyT2). PLOS ONE. 2013; 8(5): e63230.  Artículo.
3,534 Q1
2013 de Juan-Sanz, J.; Núñez, E.; López-Corcuera, B.; Aragón, C. Constitutive endocytosis and turnover of the neuronal glycine transporter GlyT2 is dependent on ubiquitination of a Cterminal lysine cluster. PLOS ONE. 2013; 8(3): e58863.  Artículo. 3,534 Q1
2012 Werdehausen, R.; Kremer, D.; Brandenburger, T.; Schlosser, L.; Jadasz, J.; Kury, P.; Bauer, I.; Aragón, C.; Eulenburg, V.; Hermanns, H. Lidocaine metabolites inhibit glycine transporter 1 a novel mechanism for the analgesic action of systemic Lldocaine? ANESTHESIOLOGY. 2012 ; 116(1) : 147-158. Article. 5,163 D1
2012 Pérez-Siles, G.; Núñez, E.; Morreale, A.; Jiménez, E.; Leo-Macías, A.; Pita, G.; Cherubino, F.; Sangaletti, R.; Bossi, E.; Ortiz, A. R.; Aragón, C.; López-Corcuera, B. An aspartate residue in the external vestibule of GLYT2 (glycine transporter 2) controls cation access and transport coupling. BIOCHEMICAL JOURNAL. 2012 ; 442(2) : 323-334. Article. 4,654 Q1
2012 Giménez, C.; Pérez-Siles, G.; Martínez-Villarreal, J.; Arribas-González, E.; Jiménez, E.; Núñez, E.; de Juan-Sanz, J.; Fernández-Sánchez, E.; García-Tardón, N.; Ibáñez, I.; Romanelli, V.; Nevado, J.; James, V. M.; Topf, M.; Chung, S. K.; Thomas, R. H.; Desviat, L. R.; Aragón, C.; Zafra, F.; Rees, M.I.; Lapunzina, P.; Harvey, R. J.; López-Corcuera, B. A novel dominant hyperekplexia mutation Y705C alters traffi cking and biochemical properties of the presynaptic glycine transporter GlyT2. JOURNAL OF BIOLOGICAL CHEMISTRY. 2012 ; 287(34) : 28986-29002. Article. 4,651 Q1
2012 Martínez-Villarreal, J.; Tardón, N. G.; Ibáñez, I.; Giménez, C.; Zafra, F. Cell surface turnover of the glutamate transporter GLT-1 is mediated by ubiquitination/deubiquitination. GLIA. 2012; 60(9): 1356-1365. Article. 5,066 Q1
2012 García-Tardón, N.; González-González, I. M.; Martínez-Villarreal, J.; Fernández-Sánchez, E.; Giménez, C.; Zafra, F.Protein kinase C (PKC)-promoted endocytosis of glutamate transporter GLT-1 requires ubiquitin ligase Nedd4-2-dependent ubiquitination but not phosphorylation. JOURNAL OF BIOLOGICAL CHEMISTRY. 2012; 287(23): 19177-19787. Article. 4,651 Q1
2011 Werdehausen, R.; Kremer, D.; Brandenburger, T.; Schlosser, L.; Jadasz, J.; Kury, P.; Bauer, I.; Aragón, C.; Eulenburg, V.; Hermanns, H. Lidocaine Metabolites Inhibit Glycine Transporter 1 A Novel Mechanism for the Analgesic Action of Systemic Lidocaine? ANESTHESIOLOGY. 2012; 116(1): 147-158. Article. 5,359 D1
2011 Jiménez, E.; Zafra, F.; Pérez-Sen, R.; Delicado, E. G.; Miras-Portugal,
M. T.; Aragón, C.; López-Corcuera, B. P2Y Purinergic Regulation of
the Glycine Neurotransmitter Transporters JOURNAL OF BIOLOGICAL CHEMISTRY. 2011; 286(12): 10712-10724. Article.
4,773 Q1
2011 Pérez-Siles, G.; Morreale, A.; Leo-Macías, A.; Pita, G.; Ortiz, A. R.;
Aragón, C.; López-Corcuera, B. Molecular basis of the differential interaction with lithium of glycine transporters GLYT1 and GLYT2. JOURNAL OF NEUROCHEMISTRY. 2011; 118(2): 195-204. Article.
4,061 Q1
2011 de Juan-Sanz, J.; Zafra, F.; López-Corcuera, B.; Aragón, C. Endocytosis
of the Neuronal Glycine Transporter GLYT2: Role of Membrane Rafts and Protein Kinase C-Dependent Ubiquitination. TRAFFIC. 2011; 12(12): 1850-1867. Article.
4,919 Q2
2011 Angelina, R.; Laura, B.; Francisco, Z.; Cecilio, G.; Guadalupe, G. A.
M. Expression of the SNAT2 amino acid transporter during the development of rat cerebral cortex. INTERNATIONAL JOURNAL
OF DEVELOPMENTAL NEUROSCIENCE. 2011; 29(7): 743-748.
Article.
 2,418 Q3
2009 Núñez, E.; Pérez-Siles, G.; Rodenstein, L.; Alonso-Torres, P.; Zafra, F.; Jiménez, E.; Aragón, C.; López-Corcuera, B. Subcellular Localization of the Neuronal Glycine Transporter GLYT2 in Brainstem. TRAFFIC. 2009; 10(7): 829-843 6.255
Q1
2009 González-González, I. M.; García-Tardón, N.; Giménez, C.; Zafra, F. Splice variants of the glutamate transporter GLT1 form hetero-oligomers that interact with PSD-95 and NMDA receptors. JOURNAL OF NEUROCHEMISTRY. 2009; 110(1): 264-274 3.999
Q2
2009 Palazzo, E.; Guida, F.; Migliozzi, A.; Gatta, L.; Marabese, I.; Luongo, L.; Rossi, C.; de Novellis, V.; Fernández-Sánchez, E.; Soukupova, M.; Zafra, F.; Maione, S. Intraperiaqueductal Gray Glycine and D-Serine Exert Dual Effects on Rostral Ventromedial Medulla ON- and OFF-Cell Activity and Thermoceptive Threshold in the Rat. JOURNAL OF NEUROPHYSIOLOGY. 2009; 102(6): 3169-3179 3.483
Q2
2009 Fernández-Sánchez, E.; Martínez-Villarreal, J.; Giménez, C.; Zafra, F. Constitutive and Regulated Endocytosis of the Glycine Transporter GLYT1b Is Controlled by Ubiquitination. JOURNAL OF BIOLOGICAL CHEMISTRY. 2009; 284(29): 19482- 19492 5.328
Q1