Presentación    
BONE PATHOPHYSIOLOGY AND BIOMATERIALS
Composition
Name
Composition
Institution
Nuria Elda Vilaboa Díaz
Investigadora Senior (Contrato Miguel Servet - I2)
Jefe de Laboratorio
Hospital Universitario La Paz
Fátima Bensiamar Hadia
Técnico de Laboratorio
Hospital Universitario La Paz - Ciber BBN
Alba Boré Medina
Técnico de Laboratorio
Hospital Universitario La Paz - Ciber BBN
Clara Escudero Duch
Investigadora Predoctoral
Hospital Universitario La Paz
Mabel Falguera Uceda
Investigadora Predoctoral
Hospital Universitario La Paz
Eduardo García Cimbrelo
Jefe de Servicio de Cirugía Ortopédica y Traumatológica A
Profesor Asociado. Departamento de Cirugía. Facultad de Medicina
Hospital Universitario La Paz
Universidad Autónoma de Madrid
Enrique Gil Garay
Jefe de Servicio de Cirugía Ortopédica
y Traumatológica B
Profesor Titular. Departamento Cirugía. Facultad de Medicina
Hospital Universitario La Paz
Universidad Autónoma de Madrid
María Gómez de Salazar Cordero
Investigadora Predoctoral 
Hospital Universitario La Paz
Carmen Martín Hervás
Facultativo Especialista de Área en
Radiodiagnóstico
Profesora Asociada. Facultad de Medicina
Hospital Universitario La Paz
Universidad Autónoma de Madrid
Francisco Manuel Martín Saavedra
Investigador Postdoctoral
Hospital Universitario La Paz - Ciber BBN
Laura Saldaña Quero
Investigadora Senior (Contrato Miguel Servet- Tipo I)
Jefe de Laboratorio
Hospital Universitario La Paz
Laura Muñoz Moreno
Investigador Postdoctoral
Hospital Universitario La Paz - Ciber BBN
Silvia Sánchez Casanova
Ayudante de Investigación 
Hospital Universitario La Paz
Gema Vallés Pérez
Investigadora Senior. Responsable de Cultivos Celulares y de los Laboratorios Comunes de IdiPAZ
Hospital Universitario La Paz
 
Strategic Objective
The Bone Physiopathology and Biomaterials group includes basic and clinical researchers from IdiPAZ. The group has broad experience in clinical and basic research on biomaterials for orthopaedic implants and bone tissue engineering. The principal goal of the group is to improve the clinical outcome of orthopaedic surgery through research on implants and biomaterials used for manufacturing prosthetic devices. The group is also interested in bone tissue engineering applications, developing surgical procedures that make use of allotransplants, evaluating scaffolds manufactured by collaborative partners and developing novel gene therapy strategies aimed to heal bone defects. Specific areas of clinical research on implants include follow-up studies on various devices in use for osteoarticular surgery.
The main areas of interest in basic research on the biocompatibility of materials include: a) understanding the influence of the surface biomaterial properties on the behaviour of bone-related cells b) the study of cell reactions occurring in the vicinity of implanted materials caused by wear particles and c) the deliberate manipulation of cell responses after exposure to nanoparticles designed for gene delivery and optical hyperthermia applications.
The team is also interested in the development of transcriptional targeting strategies to ensure tight control of the expression of therapeutic proteins and their potential application in inducing an orchestrated expression of growth factors .involved in bone healing.
Research Lines
• Clinical research in implants for bone repair
• Biocompatibility of new materials for potential use in implants for bone repair: cell and surface interactions, cell and particle interactions
• Control of the expression of therapeutic genes using gene circuits