Presentación    
VASCULAR PHYSIOLOGY AND PHARMACOLOGY
 
Excellence Group
Composition
Name
Position
Institution
Mercedes Salaices Sánchez
Catedrática. Departamento de Farmacología.
Facultad de Medicina
Universidad Autónoma de Madrid
0000000Andrea0000000 Aguado Martínez
Investigadora Postdoctoral
Universidad Autónoma de Madrid
María Jesús Alonso Gordo
Catedrática. Departamento de Ciencias Básicas de la Salud. Facultad de Ciencias de la Salud
Universidad Rey Juan Carlos
María Soledad Avendaño Herrador
Investigador Postdoctoral
Universidad Autónoma de Madrid
Gloria Balfagón Calvo
Catedrática. Departamento de Fisiología. Facultad de Medicina
Universidad Autónoma de Madrid
Javier Blanco Rivero
Profesor Contratado Doctor. Departamento de Fisiología. Facultad de Medicina
Universidad Autónoma de Madrid
Ana María Briones Alonso
Investigadora Senior (Contrato Ramón y Cajal)
Universidad Autónoma de Madrid
Laura Caracuel Cano
Investigadora Postdoctoral
Universidad Autónoma de Madrid
Ana Belén García Redondo
Investigadora Postdoctoral
Universidad Autónoma de Madrid
María González Amor
Investigadora Predoctoral
Universidad Autónoma de Madrid
Raquel Hernanz Martín
Profesora Contratada Doctor. Departamento de Ciencias Básicas de la Salud. Facultad de Ciencias de la Salud
Universidad Rey Juan Carlos
Ángela Martín Cortes
Profesora Contratada Doctor.
Departamento de Ciencias de la Salud. Facultad de ciencias de la Salud
Universidad Rey Juan Carlos
Marta Miguel Castro
Investigadora Postdoctoral
Instituto de Investigación en Ciencias de la Alimentación. Consejo Superior de Investigaciones Científicas
Roberto Palacios Ramírez
Investigador Predoctoral
Universidad Rey Juan Carlos
Raquel Rodrígues Díez
Investigadora Postdoctoral
Universidad Autónoma de Madrid
Strategic Objective
Our group is a well-established research group with more than 30 years of experience in the study of the mechanisms involved in the functional, structural and mechanical alterations of the vasculature in various cardiovascular pathologies such as ageing, diabetes and, in particular, hypertension.
The group is located at the Faculty of Medicine (UAM) and maintains research collaborations with investigators at various universities in Spain and in other countries. Our main objective is to gain further insight into the physiological and molecular mechanisms involved in alterations of resistance and conductance arteries in cardiovascular pathologies. To conduct our research, we generally use various experimental approaches including in vivo animal models, ex vivo experiments and in vitro cellbased studies combined with physiological, pharmacological and molecular biology techniques. In addition, we have begun to translate this knowledge into human studies. In terms of the mediators involved, we have a particular interest in the role of prostanoids derived from the inducible isoform of cyclooxygenase (COX-2) and reactive oxygen species (and their interaction among each other or with other mediators such as nitric oxide) in inflammatory conditions that resemble those found in cardiovascular pathologies. This research is important given the essential role these mediators play in the control of vascular smooth muscle tone and vascular structure.
Research Lines
• Oxidative stress, COX-derived products and vascular function and remodelling. Changes with hypertension and other cardiovascular pathologies.
• Adipose tissue and vascular alterations in cardiovascular pathologies.
• Neural control of vascular tone.
• Cardiovascular effects of heavy metals.
• Antioxidant and antihypertensive properties of bioactive peptides.